| 2010, Cilt 32, Sayı 2, Sayfa(lar) 097-102 |
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| Factors Affecting Prognosis in Upper Urinary System Urothelial Tumors: 15 Years’ Clinical Experience |
| Abdullah Demirtaş, Nurettin Şahin, Oğuz Ekmekçioğlu, Mustafa Sofikerim, Atila Tatlışen |
| Department of Urology Erciyes University Medical School, Kayseri, Turkey |
| Keywords: Transitional Cell Carcinoma; Kidney; Prognosis; Ureter |
Purpose: It is aimed to determine retrospectively evaluate oncological results of cases with
upper urinary system urothelial tumors in our clinic for the last 15 years.
Material and Methods: Records of 32 cases in our clinic January 1992-December 2006 were
evaluated retrospectively. Evaluated parameters are age, complaint; tumor localization, grade
and stage, applied treatment choice, follow-up period, lifetime without illness, time until tumor
recurrence.
Results: Median age was 60 (30-82 years), mean follow-up period was 23 months (3-118
months). In follow-up period, tumor recurred in fourteen cases. Tumor was defined as low
and high grades in twenty two (69%) (%68,75) and ten (31%) (%31,25) cases, respectively;
and tumor was determined in fourteen (44%) (%43,75), five(16%) (%15,63), six(18%)
(%18,75), five(16%) (%15,63) and two cases (6%) (%6,26), in Ta, T1, T2, T3, T4 stages,
respectively. Seven patients (22%) (%21,88) are still alive and mean follow-up period is 39
months (11-118 months). Nineteen patients (60%) (%59,38) whose mean follow-up period
was 24 months (0.5-56 months) died because of the illness. When their durations of survival
are considered, it was found there was a statistically significant difference between tumor
stage and survival duration and that, however, there was no meaningful difference between
tumor grade and survival duration.
Conclusion: Tumor stage was defined as the most important prognostic factor for upper
urinary system urothelial tumors.
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