This study was performed in 30 children, ASA physical
status I or II and undergoing elective non-ophthalmic
surgery, approved by Erciyes University, Medical Faculty
Ethical Committee and informed consent by the parent
of children. The children were aged between 12-84 months.
Premedication was omitted. In the operating room, HR,
non-invasive ABP, peripheral oxygen saturation (SpO
2)
(Datex-Engstrom AS/3, Finland) were monitored for the
children. After endotracheal intubation, gases for
measurements were sampled from the angle piece placed
at the distal end of the tracheal tube. Anesthesia was
induced with sevoflurane 8% in 66% N
2O and O
2 in all
children via facemask with Mapleson B circuit for all children. Following the anesthesia induction, laryngoscopy
and endotracheal intubation was performed by the same
anesthetist after the pupils are centered. Anesthesia was
maintained with 2.5-3% sevoflurane in 66% N
2O and O
2
with semi-closed pediatric anaesthesic system for all
children. IOP measurements were performed by same
chief ophtalmologist. A Schiötz tonometer was used to
measure the IOP. Two readings were taken in the right
and left eye at each measurement time, the mean of the
two readings was recorded. In all children, caudal blockade
was performed for postoperative analgesia after tracheal
intubation and IOP measurements. IOP was measured
first after induction, then 1, 3, 5 min after intubation, and
just 1 min before and 1, 3 min after extubation. Because
of difficulties in unpremedicated children, IOP was not
measured preoperatively. HR, ABP, SpO
2 values were
recorded after anesthesia induction, just before application
of i.v. cannulae; after intubation 1
st, 3
rd and 5
th minute,
just before extubation and 1, 3 and 5 minute later. At the
end of operation, when the skin closure was started, N
2O
administration was terminated, 1-1.5% sevoflurane in
100% O
2 was continued. The children were extubated
after return of spontaneous ventilation and sevoflurane
vapourizer closed.
Results are expressed as mean±standard deviation
(mean±SD). A repeated measure of ANOVA was used
for serial data the changes of IOP, HR, sistolic blood
pressure (SBP), diastolic blood pressure (DBP) and p<0.05
was considered statistically significant.
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